解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
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生理学
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热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The use of summary rates of reporting health data is discussed. Directly and indirectly adjusted rates are compared under two models of no interaction. A method of analysis is described whereby a model is first fitted to data in order to investigate assumptions, and subsequently the smoothed rates based on the model a...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract::Several models for the course of microbial infections during the incubation period are examined. Each model fits sore throat incubation data very well. Together with the lack of precision of the resulting parameter estimates, this suggests that incubation data alone are insufficient for elucidating the finer details o...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract::This paper presents the development, application and evaluation of a stochastic model of the frequency of occurrence of transient ischemic attacks (TIAs). TIAs occur during periods of abnormal arterial activity. The TIAs which occur during a single period of abnormal activity are called a cluster of TIAs. Thus, the nu...
journal_title:Biometrics
pub_type: 临床试验,杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::The class of admissible tests for Hardy-Weinberg equilibrium in a multi-allelic system is characterized. The standard goodness-of-fit chi-square tests is shown to be admissible for systems of two or more alleles. The conditional probability distribution required to determine the exact significance level of this test i...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::The concentration of carbon monoxide in the blood of a cigarette smoker varies in response to the frequency and dose of CO delivered by the cigarettes he smokes and by the rate at which CO washes out of his blood. Moments of first passage times or exit times above a nominal threshold can be calculated using a stochast...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1979-09-01 00:00:00
abstract::The basic technical facts of human cytogenetics and the laboratory methods employed in chromosome research are explained in simple terms. The main variables used to describe chromosome images are defined and discussed. Three discriminant analysis models for chromosome classification are developed: one in which each ch...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract::In matched case-control studies one frequently must consider more than one variable in the analysis and in this paper a log-linear model is presented to meet this objective. A conditional argument yields a method for making inferences on the parameters measuring the association between the variables and disease. The r...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1978-12-01 00:00:00
abstract::A likelihood ratio statistic is proposed for testing goodness of fit with grouped data which are subject to random right censoring. It is shown that, under appropriate conditions, this statistic has an asymptotic chi-square distribution which is non-central under contiguous alternatives. A formula is given for the non...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1978-09-01 00:00:00
abstract::An efficient method is presented for analyses of death rated in one-way or cross-classified experiments where expected survival time for a patient at time of entry on trial is a function of observable covariates. The survival-time distribution used is a Weibull form of Cox's (1972) model. The analysis proceeds in two ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1978-06-01 00:00:00
abstract::Assuming a model of proportional failure rates, Cox (1972) presents a systematic study of the use of covariates in the analysis of life time. The treatment of tied observations is a particularly troublesome point in both theory and application. It appears that grouping rather than discrete time is the right way to han...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1977-09-01 00:00:00
abstract::This paper is concerned with the analysis of multivariate categorical data which are obtained from repeated measurement experiments. An expository discussion of pertinent hypotheses for such situations is given, and appropriate test statistics are developed through the application of weighted least squares methods. Sp...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1977-03-01 00:00:00
abstract::In this paper, a Markov process is developed as a mathematical model to study the general problem of quality control monitoring. This approach was previously used by Arnold (1970) in development of sampling plans to study the water quality monitoring of streams. Arnold considered the expected sample size required for ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1977-03-01 00:00:00
abstract::The estimation of maternal genetic variances by a multivariate maximum likelihood method is discussed. As an illustration the method is applied to data on Tribolium using a model based on partitioning the maternal genetic effect into additive and dominance components. An alternative model due to Falconer (1965) is als...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1976-12-01 00:00:00
abstract::In clinical trials and other investigations of survival time, information is often available on a time-dependent event other than survival. An example of such an auxiliary event in cancer studies is objective progression of disease. While some patients expire without experiencing objective disease progression, others ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::In sampling certain types of materials, such as bags of fertilizer, or subsampling large quantities of water, as might be done in investigating the density of plankton in certain environmental situations, it is customary to composite the samples. That is, several samples are drawn, mixed into a composite sample, and a...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1976-06-01 00:00:00
abstract::The matrix considered contains four elements, each a function of total number. A special case for which the matrix may be appropriate is when the population may be divided into juveniles and adults, and the survival rates and fecundity are the same for all members of each group. This is true, at least approximatley, f...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1976-06-01 00:00:00
abstract::A life table estimates probabilities of surviving and of dying as well as death rates, as these would apply in a stationary population with the same underlying continuous mortality curve as the observed population. We have derived approximations to the probability of surviving that require no iteration, do not depend ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1975-12-01 00:00:00
abstract::Let Yi be an ni X 1 vector of observations, Xi an ni X p matrix of known values, and beta an unknown p X 1 with the structure Yi = Xi beta + epsilon i, where the covariance matrix of epsilon i is of intra-class form, that is Cov (epsilon i) = sigma2[(1 - rho) Ii + rho e i e i'] where Ii is the ni X ni identity matrix ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
abstract::In controlled clinical trials there are usually several prognostic factors known or thought to influence the patient's ability to respond to treatment. Therefore, the method of sequential treatment assignment needs to be designed so that treatment balance is simultaneously achieved across all such patients factor. Tra...
journal_title:Biometrics
pub_type: 临床试验,杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::Procedures for estimating the genetic parameters of plant populations frequently employ progeny testing to ascertain the genotype of maternal plants. However, when experimental resources are limited (e.g., electrophoretic markers), the large progeny sizes required for accurate typing severely restricts the numbers of ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::In this study we are concerned with the construction of confidence intervals for the conditional probability of misallocation associated with Anderson's classification statistics, W. The available methods of computing confidence intervals for the conditional probability are not satisfactory in practice, mainly because...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00